Congratulations to Angel for publishing his paper on chromatin remodeling at the onset of reprograming in Cell Reports. Read the paper here: https://www.cell.com/cell-reports/fulltext/S2211-1247(24)00498-4
Adriana wins the 1st Place Poster Award
Congratulations to Adriana for winning the 1st Place Poster Award at the Dr. George Raiziss 39th Annual Retreat of the Department of Biochemistry and Biophysics!
Our paper on microtubule detyrosination is now online in Current Biology!
Check out how cells enrich detyrosination marks on a subset of microtubules. Congratulations to all authors, particularly Qing Tang from the lab. Extra thanks to our computational collaborators, Sebastian Sensale and Gaurav Arya! https://www.sciencedirect.com/science/article/abs/pii/S0960982223015063
Congratulations Hannah and Ellen!
Congratulations to Hannah and Ellen for being awarded a pilot grant by the Center for Engineering Mechanobiology for their studies on mechanical regulation of chondrocyte fate!
Welcome Victor Xing!
Lakadamyali lab keeps growing. We are pleased to welcome Victor, who has decided to join the lab as a PhD student after having completed his rotation in the lab!
Welcome Marcus Woodworth
A belated welcome to Marcus Woodworth, who joined the lab in April as a postdoctoral fellow!
Triple celebration in the Lakadamyali Lab
We celebrated Jose-Angel Martinez Sarmiento successfully defending his thesis! Hannah Kim passed her prelims with flying colors to officially become a PhD candidate. And Adriana Naomi Santiago-Ruiz got her NIH F31 fellowship funded! What a week! Congratulations to Angel, Hannah and Adriana!
Lakadamyali Lab goes to the Biophysical Society Meeting in San Diego
The lab was well-represented at the BPS meeting in San Diego with two platform talks by Adriana and Patty and two poster presentations by Charlie and Siewert. They all did an amazing job! Congratulations!
Welcome Solon Andrades Da Rosa
We have a new visiting PhD student from the ICBS/UFRGS in Brazil. Solon will study the heterogeneity of senescent cells in glioblastoma cancer using super-resolution microscopy. We are excited to have him in the lab
Our collaboration with the Svitkina lab in Nature Comms
Congratulations to Patty and Siewert who contributed to a collaborative project on actin’s role in clathrin mediated endocytosis in collaboration with Tanya Svitkina’s lab at Penn. Read the paper here: https://www.nature.com/articles/s41467-022-33852-2
Our paper on the impact of chemomechanical cues on chromatin in Nature BME
Our collaborative work with the labs of Su Chin Heo, Rob Mauck, Vivek Shenoy and Jason Burdick showing how degenerative chemomechanical cues in disease impact chromatin spatial organization is out in Nature Biomedical Engineering. Congratulations to all authors. This has been a fun collaboration. Read here the paper:
https://www.nature.com/articles/s41551-022-00910-5?fbclid=IwAR1vFx75OCEOTHfYchn2IRZHXKWoNYdhsnr-5KKRmf41u1qMO0va0V68MvI
And the highlight in Penn Medicine News:
https://www.pennmedicine.org/news/news-releases/2022/august/the-locked-library-disease-causes-cells-to-reorder-their-dna-incorrectly?fbclid=IwAR3qva_SZlUHogG6LdVeLNwxj-fxq8mUNFIZoqgeRTMeUbZklC5hoL2uUDg
Welcome Hannah Kim!
Lakadamyali lab is happy to welcome Hannah Kim from the BMB Graduate Group who officially joined the lab as a PhD student.
Big Weekend in the Lakadamyali lab
Lakadamyali lab had a double celebration over the long 4th of July weekend. We celebrated Melina’s wedding - Congratulations Melina and Nick - and we celebrated the arrival of Angel’s baby on the very same day, Dara Valentina - Congratulations Angel and Yazmin -
Congratulations Dr. Gyparaki
Big congratulations to Melina Gyparaki, the first student to join the Lakadamyali lab at Penn, for successfully defending her thesis and becoming the first Penn graduate of the Lakadamyali lab. We are very proud of what you have accomplished over these years!
Angel wins first place poster award!
Congratulations to Angel who won the first place poster award at the IRM retreat. Angel was up against some tough competition and came out ahead. Great job Angel!
Congratulations Siewert!
Siewert's paper from the LASIRE lab (University of Lille, France) was selected for the Editor's choice for Super-resolution microscopy collection in Scientific Reports. Congratulations Siewert!
Open Postdoc Positions
We have open postdoc positions to work at the interface of advanced microscopy and cell biology of intracellular transport, protein aggregates and the nucleus. Interested individuals should email their CV and cover letter to Melike.
Our new review paper out in Molecular Cell!
January 2022 — Our new review paper on super-resolution is out in Molecular Cell. Huge congratulations to Charlie, Adriana and Qing on the big effort that made this review possible. You can check it out here: https://www.sciencedirect.com/science/article/pii/S1097276521010844?via%3Dihub
Welcome Siewert!
September 13, 2021 — We welcome Siewert Hugelier to the lab. Siewert will continue Arian’s legacy on the development of computational tools for super-resolution microscopy and single molecule imaging. We are thrilled to have him join the team!
Goodbye Arian!
August 27, 2021 — We are sad to say goodbye to Arian Arab but excited for his next steps and his transition to the FDA. Arian made a huge impact to the lab’s computational development efforts during his time in the lab and he will be missed!